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Fasting Required: No
Turnaround Time: 2-10 business days
Specimen Type: Blood
ZPP, free erythrocyte protoporphyrin (FEP) blood test, ZP test, ZPP/heme ratio
Your physician will order a ZPP blood test to evaluate chronic lead exposure and iron deficiency.
The ZPP test measures zinc protoporphyrin or ZPP, a substance formed when heme is produced. Heme is the precursor to hemoglobin – a significant part of the red blood cell (RBC) that transport oxygen in the body.
Zinc protoporphyrin is typically found in small amounts in the blood. However, its concentration increases with high exposure to lead and when serum iron is insufficient. Thus, a ZPP blood test often becomes part of an immediate medical intervention against lead poisoning or regular work hazard monitoring. Also, it goes hand-in-hand with a lead blood test.
Among children and pregnant women, it’s often used to help screen for iron deficiency anemia together with other tests, such as the TIBC blood test, anemia profile blood test, and a comprehensive iron profile test.
People who work closely with lead (manufacturing, construction, and related industries) should consider getting tested to measure their exposure to the element. More so if the following symptoms of lead poisoning are observed.
Furthermore, take a ZPP test if you experience signs and symptoms of iron deficiency anemia, which include:
No special preparation is necessary before the blood sample collection.
Test values that exceed 35 micrograms per deciliter (mcg/dL) suggest high levels of lead, which prevents heme production. Below this figure, ZPP levels are considered normal. However, the reference range may vary slightly depending on the laboratory. Therefore, it’s best to check the assigned reference interval for accurate comparison.
You can get the ZPP test through the following steps.
Step 1: Hover over to our website’s heavy metal testing section, and order the ZPP blood test. Then, download the lab test order, which will serve as your doctor’s order for when you take the test.
Step 2: Select your preferred partner medical center through our lab locator.
Step 3: Head to the laboratory you chose and had your blood collected.
Step 4: Expect the lab test results within 2-10 business days in your Personalabs account.
For an exact turnaround time for results, don’t hesitate to contact us at 1-888-438-5227. We will contact the lab of your choice (Quest Diagnostics or LabCorp) as turnaround times vary depending on testing location or lab testing provider.
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Get Your Results
Results can be provided in as little as 24-48 hrs. For more complex tests, please contact us for turn around times.
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I appreciated the quick turnaround from the time I ordered the laread more
Review of 5/16/2025, reflecting an experience on 5/14/2025 by Patricia S
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Review of 4/19/2025, reflecting an experience on 4/10/2025 by Brian B
I appreciated the quick turnaround from the time I ordered the laread more
Review of 5/16/2025, reflecting an experience on 5/14/2025 by Patricia S
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Great service provides easy access to routine wellness and other read more
Review of 4/19/2025, reflecting an experience on 4/10/2025 by Brian B