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HLA B27 Antigen Blood Test

* This is not a home test kit. You will need to visit a local lab for testing.

Also Known As

Histocompatibility Leukocyte A Antigen, Human Leukocyte A Antigen, Human Lymphocyte Antigen B27

The Purpose of an HLA B27 Test

Your white blood cells are important immune system defenders in the fight against germs and disease. But if you have the human leukocyte antigen B27 (HLA B27) on the surface of your white blood cells, that can lead to autoimmune diseases characterized by inflammation and painful joints, including reactive arthritis and ankylosing spondylitis, as well as another condition, anterior uveitis, with inflammation that damages the eyes.

HLA-B27 Antigen (528)
HLA-B27 Disease Association (006924)

What Does the HLA B27 Blood Test Measure?

A human leukocyte antigen B27 test determines if you have this antigen in your blood.

Who Should Take a Human Leukocyte Antigen B27 Test?

If you’re experiencing unexplained joint pain, particularly in the back and neck, then you may need to be tested for HLA B27.

HLA B27 Testing Preparation

You don’t have to follow any special instructions to prepare for the HLA B27 antigen test.

HLA B27 Test Results

Test results come back either positive or negative. A positive test confirms that you have the HLA B27 antigen. This may require further investigation, which can include blood, urine, and imaging tests (including x-rays and MRIs). If you need a physician to consult with about a positive HLA B27 test result, we’re here to help you by offering convenient telehealth appointments with one of our board-certified physicians.

Where Can I Get an HLA B27 Blood Test Near Me?

We provide easy access to HLA B27 testing. This test is one of more than 400 we offer online, and when it comes time to take it, you can choose from more than 4,000 labs across the country, thanks to our affiliations with leading lab companies Quest Diagnostics and Labcorp.

Here’s just how simple it is to take control of your health with Personalabs:

Step 1: Once you’ve purchased the test you want, download the appropriate lab order. (And you may not even need a doctor’s approval to buy and take the test, depending on the state where you live.)

Step 2: Schedule your blood draw by using our locator tool to pinpoint the lab near you.

Step 3: Complete your blood work at the lab. (Be sure to bring the test order to the lab with you.)

Step 4: Review your results in your secure Personalabs account. The test report typically arrives within 2 to 10 business days after your testing date. (Need the results back by a specific date? Contact us, and we can work with the lab on making that turnaround time happen for you.)

When it comes to healthcare, Personalabs puts the power in your hands. Explore the full range of tests today.

Additional information


LabCorp, Quest

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Order Your Test

Create an account, choose your tests, checkout securely, generate your lab order



Generate & Print Out Lab Order

Our physician network will approve your order within 2-4hrs.



Visit the Lab

The test price decides which lab you will visit: Quest or Labcorp. Find a location in your area.



Get Your Results

Results can be provided in as little as 24-48 hrs. For more complex tests, please contact us for turn around times.


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