๐ฉบ Medically Reviewed by: Edward Salko, D.O. | ๐ Updated: May 2026 | ๐ณ HSA/FSA Eligible | ๐งช Includes Progesterone & Estradiol
The Foundation of Hormonal Vitality for Women
Don’t guess about your cycle, energy, or mood. The Comprehensive Female Hormone Profile is a deep-dive assessment designed to provide clarity. Whether you are navigating perimenopause, tracking fertility, or troubleshooting weight changes, this panel delivers the data you need to reclaim your health.
What This Profile Uncovers:
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Estrogen (Estradiol) & Progesterone: The core markers for understanding your cycle, bone health, and mood stability.
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Testosterone (Free & total): Often overlooked in women, testosterone is critical for libido, cognitive clarity, and muscle maintenance.
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DHEA-S & Cortisol: Insight into your adrenal health and how your body is coping with chronic stress.
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TSH (Thyroid): Screens for thyroid imbalances that are often the hidden cause of weight gain and hair thinning.
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FSH & LH: Essential for determining your reproductive stage and ovulation health.
Who Needs the Comprehensive Female Hormone Profile
This panel is designed for three specific clinical situations where basic hormone testing is insufficient:
Complex PCOS evaluation โ PCOS has four recognized phenotypes and the hormonal pattern varies between them. The LH/FSH ratio above 2:1 is the classic PCOS pattern. Elevated total testosterone with elevated LH and normal FSH points toward ovarian androgen excess. Elevated testosterone with normal LH/FSH suggests adrenal contribution.
The comprehensive profile captures all these patterns โ a standalone testosterone or estradiol test cannot.
Thyroid plus hormone overlap โ thyroid dysfunction causes symptoms identical to hormonal imbalance. Fatigue, irregular
periods, weight gain, hair loss, and mood changes can come from low thyroid, PCOS, perimenopause, or all three simultaneously. Testing TSH and Free T4 alongside the reproductive hormones in a single draw identifies which system is driving the symptoms โ or confirms they are working together.
Post-menopausal estrogen assessment โ after menopause estrone (E1) becomes the dominant estrogen as estradiol (E2)
falls. Estrogens Total captures this shift that estradiol alone misses. Women on bioidentical HRT containing estriol
specifically need total estrogens testing โ estradiol alone does not reflect their full hormonal replacement status.
All in a single Labcorp blood draw. No doctor required.
Reviewed by Edward Salko, D.O., Medical Director, Personalabs
Use:
A more advanced profile of hormones can help identify the cause of a woman’s menstrual, fertility, sexual or overall health and wellness problems.
Includes: FSH and LH, Thyroid Profile with TSH, Total Testosterone(Highly Sensitive), Estradiol, Estrogen.
Recommended For:
Women concerned with menstrual, fertility, sexual or overall health problems.
Special Notes:
If you are currently taking a thyroid hormone, it is recommended you get your blood drawn prior to taking your daily dose. Otherwise, no special preparation is needed for thyroid bloodwork.
Clinical Review: Dr. Edward Salko
Edward Salko, D.O., Medical Director at Personalabs: “For many women, standard ‘normal’ ranges on a lab report don’t reflect how they actually feel. This Comprehensive Profile is vital because it looks at the interplay between Progesterone and Estrogen. Finding that balance is often the key to solving issues like brain fog, sleep disturbances, and persistent fatigue.”
Tests Included:
Thyroid Profile with TSH (000620)
Estrogens, Total (004549)
FSH and LH (028480)
Testosterone, Total , LC/MS-MS (Women and Hypogonadal Males) (070001)
Estimated Turn Around For Results:
2-10 Business Days
For an exact turnaround time for results, please contact us at Personalabs and we will contact the lab on your behalf as turnaround times vary depending on testing location or lab testing provider.
Frequently Asked Questions: Comprehensive Female Hormone Profile
What is included in the Comprehensive Female Hormone Profile?
The Comprehensive Female Hormone Profile includes FSH, LH, TSH, Free T4, Total Testosterone (Highly Sensitive), Estradiol (E2), and Estrogens Total (E1+E2+E3). This combination evaluates pituitary function, ovarian hormone production, thyroid status, and androgen levels โ the complete hormonal picture in a single blood draw.
How is this different from the Basic Female Hormone Profile?
The Comprehensive Profile adds TSH, Free T4, Estrogens Total, and Highly Sensitive Total Testosterone to the basic panel. It is designed for complex presentations โ PCOS evaluation, thyroid-hormone overlap, post-menopausal women on bioidentical HRT, and anyone with persistent hormonal symptoms despite normal basic hormone results.
When should I get my blood drawn for this test?
For fertility or PCOS evaluation draw on day 3 of your menstrual cycle โ day 1 being the first day of full flow. For perimenopause or menopause evaluation timing is less critical. If you take thyroid medication draw before your morning dose for the most accurate TSH and Free T4 reading. No fasting required.
Can I order this without a doctor?
Yes. Personalabs provides the physician-approved lab order with your purchase. Order online, visit any Labcorp patient service center near you, results in 24 to 48 hours. No referral required. HSA and FSA eligible.
